P2X7 modulators
The present invention is directed to compounds of Formulas (1, la, lla and lib): o R3 Rf N N "X Formula (1) & Formula (la) o R3 R6 0 R3 Re N Re 8 R N N N-R6 Formula (Ila) Formula (l1b) The invention also relates to pharmaceutical compositions comprising compounds of Formulas (1, la, Ila and...
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| creator | ANDRES GIL, Jose Ignacio ALCAZAR VACA, Manuel Jesus SAVALL, Brad M CHROVIAN, Christa C DENG, Xiaohu SWANSON, Devin M ALLISON, Brett D DVORAK, Curt A LETAVIC, Michael A COATE, Heather R STENNE, Brice M MANI, Neelakandha S SOYODE-JOHNSON, Akinola WALL, Jessica L GELIN, Christine F DE ANGELIS, Meri RECH, Jason C LIANG, Jimmy T |
| description | The present invention is directed to compounds of Formulas (1, la, lla and lib): o R3 Rf N N "X Formula (1) & Formula (la) o R3 R6 0 R3 Re N Re 8 R N N N-R6 Formula (Ila) Formula (l1b) The invention also relates to pharmaceutical compositions comprising compounds of Formulas (1, la, Ila and lIb). Methods of making and using the compounds of Formulas (1, la, Ila and lib) are also within the scope of the invention. |
| format | Patent |
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Methods of making and using the compounds of Formulas (1, la, Ila and lib) are also within the scope of the invention.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240404&DB=EPODOC&CC=AU&NR=2024201709A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240404&DB=EPODOC&CC=AU&NR=2024201709A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ANDRES GIL, Jose Ignacio</creatorcontrib><creatorcontrib>ALCAZAR VACA, Manuel Jesus</creatorcontrib><creatorcontrib>SAVALL, Brad M</creatorcontrib><creatorcontrib>CHROVIAN, Christa C</creatorcontrib><creatorcontrib>DENG, Xiaohu</creatorcontrib><creatorcontrib>SWANSON, Devin M</creatorcontrib><creatorcontrib>ALLISON, Brett D</creatorcontrib><creatorcontrib>DVORAK, Curt A</creatorcontrib><creatorcontrib>LETAVIC, Michael A</creatorcontrib><creatorcontrib>COATE, Heather R</creatorcontrib><creatorcontrib>STENNE, Brice M</creatorcontrib><creatorcontrib>MANI, Neelakandha S</creatorcontrib><creatorcontrib>SOYODE-JOHNSON, Akinola</creatorcontrib><creatorcontrib>WALL, Jessica L</creatorcontrib><creatorcontrib>GELIN, Christine F</creatorcontrib><creatorcontrib>DE ANGELIS, Meri</creatorcontrib><creatorcontrib>RECH, Jason C</creatorcontrib><creatorcontrib>LIANG, Jimmy T</creatorcontrib><title>P2X7 modulators</title><description>The present invention is directed to compounds of Formulas (1, la, lla and lib): o R3 Rf N N "X Formula (1) & Formula (la) o R3 R6 0 R3 Re N Re 8 R N N N-R6 Formula (Ila) Formula (l1b) The invention also relates to pharmaceutical compositions comprising compounds of Formulas (1, la, Ila and lIb). 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Methods of making and using the compounds of Formulas (1, la, Ila and lib) are also within the scope of the invention.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | P2X7 modulators |
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