Materials and methods for treatment of apolipoprotein c3 (APOCIII)-related disorders

Abstract The present application provides materials and methods for treating a patient with dyslipidaemia and/or other diseases associated with APOCIII, both ex vivo and in vivo. In addition, the present application provides materials and methods for genome editing to modulate the expression, functi...

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Hauptverfasser: Kulkarni, Samarth, Klein, Lawrence, Padmanabhan, Hari Kumar, Lundberg, Ante Sven
Format: Patent
Sprache:eng
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Zusammenfassung:Abstract The present application provides materials and methods for treating a patient with dyslipidaemia and/or other diseases associated with APOCIII, both ex vivo and in vivo. In addition, the present application provides materials and methods for genome editing to modulate the expression, function, or activity of an Apolipoprotein C3 (APOCIII) gene in a cell.