HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF
The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof; N'R1 R4 i wherein R 1 R2 , R 4 and X 1 are defeined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combi...
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creator | CULSHAW, Andrew James MILTZ, Wolfgang ROEHN, Till BUSHABOINA, Mallesh WÄLCHLI, Rudolf HURLEY, Timothy Brian PATEL, Tajesh CHEN, Xin SANDHAM, David Andrew RAJAGOPALAN, Srinivasan ORAIN, David THOMA, Gebhard TICHKULE, Ritesh Bhanudasji LABBE-GIGUERE, Nancy CHEUNG, Atwood Kim |
description | The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof; N'R1 R4 i wherein R 1 R2 , R 4 and X 1 are defeined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF |
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