HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF

The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof; N'R1 R4 i wherein R 1 R2 , R 4 and X 1 are defeined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combi...

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Bibliographische Detailangaben
Hauptverfasser:	CULSHAW, Andrew James, MILTZ, Wolfgang, ROEHN, Till, BUSHABOINA, Mallesh, WÄLCHLI, Rudolf, HURLEY, Timothy Brian, PATEL, Tajesh, CHEN, Xin, SANDHAM, David Andrew, RAJAGOPALAN, Srinivasan, ORAIN, David, THOMA, Gebhard, TICHKULE, Ritesh Bhanudasji, LABBE-GIGUERE, Nancy, CHEUNG, Atwood Kim
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof; N'R1 R4 i wherein R 1 R2 , R 4 and X 1 are defeined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.