NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR

The present invention provides a novel linker compound and a ligand-drug conjugate therefor. This can stably deliver an active ingredient to a target site and rapidly release the active ingredient at the target site, and thus can increase efficacy of the active ingredient and can prevent the active...

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Bibliographische Detailangaben
Hauptverfasser:	MIN, Gyoung Wook, CHO, Jong Un, LEE, Hyun Mi, WOO, Sung Ho, PARK, Ok Ku, PARK, Su Ho, YUN, Sang Hyeon
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS SUGARS
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Beschreibung
Zusammenfassung:	The present invention provides a novel linker compound and a ligand-drug conjugate therefor. This can stably deliver an active ingredient to a target site and rapidly release the active ingredient at the target site, and thus can increase efficacy of the active ingredient and can prevent the active ingredient from causing side effects at locations other than the target location.