IL-12 VARIANTS, ANTI-PD1 ANTIBODIES, FUSION PROTEINS, AND USES THEREOF

IL-12 variants are provided. Also provided are antibodies that specifically bind to PD1. Also provided are fusion proteins of IL-12 variants and anti-PD1 antibodies. Also provided are uses of these IL-12 variants, anti-PD1 antibodies, fusion proteins, and related compositions and methods.

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Bibliographische Detailangaben
Hauptverfasser:	APGAR, James Reasoner, STARBECK-MILLER, Gabriel Roy, ZAJONC, Dirk Michael, MOSYAK, Lidia, PASCUA, Edward Derrick, MOHAN, Kritika, HUANG, Tzu-Hsuan, CHU, Ling Hon Matthew, PATTERSON, James Travis, CHAPARRO RIGGERS, Javier Fernando
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	IL-12 variants are provided. Also provided are antibodies that specifically bind to PD1. Also provided are fusion proteins of IL-12 variants and anti-PD1 antibodies. Also provided are uses of these IL-12 variants, anti-PD1 antibodies, fusion proteins, and related compositions and methods.