KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE

KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE

Provided herein are optionally substituted benzoimidazol-1,2-yl amides, pharmaceutical compositions comprising a therapeutically effective amount of such compounds and a pharmaceutically acceptable excipient, and methods of treating Kv7 associated diseases, such as, epilepsy, amyotrophic lateral scl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Charles A. FLENTGE, Lynn RESNICK, James S. HALE, David A. MARESKA, Justin K. BELARDI, Michael E. BOZIK, Scott S. HARRIED, George T. TOPALOV
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided herein are optionally substituted benzoimidazol-1,2-yl amides, pharmaceutical compositions comprising a therapeutically effective amount of such compounds and a pharmaceutically acceptable excipient, and methods of treating Kv7 associated diseases, such as, epilepsy, amyotrophic lateral sclerosis, various types of pain, hyperexcitability, a dyskinesia, dystonia, mania and tinnitus with such compounds and pharmaceutical compositions.