EPIGENETIC MARKERS FOR DETECTING OXIDATIVE STRESS

The present invention is related to a method of identifying oxidative stress (OS) in a test cell, the method comprising: (a) determining the methylation status of at least five genes in a DNA sample obtained from the test cell; (b) comparing the methylation status of the genes from step (a) to the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	NAGARAJAN, Sanjanaa, BÖHL, Florian, BOURLAND, Jennifer, ROY, Suki
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is related to a method of identifying oxidative stress (OS) in a test cell, the method comprising: (a) determining the methylation status of at least five genes in a DNA sample obtained from the test cell; (b) comparing the methylation status of the genes from step (a) to the methylation status of the corresponding genes in a control without OS, wherein a difference in the methylation status of the genes in the test cell compared to the corresponding genes in the control is indicative of the cell having OS; and wherein the genes in step (a) are selected from the group consisting of