BCL6 inhibitors

1UU4 J0/U93 The present invention relates to compounds of formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: HN l Formula I wherein X1, X2 , R 1, R2 , R3 0, R31 and Ring A are each as defined herein. The present invention also relates to processes for the preparation of thes...

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Bibliographische Detailangaben
Hauptverfasser:	Rosemary Huckvale, Mirco Meniconi, Matthew Garth Lloyd, Swen Hoelder, Gavin Collie, Kwai Ming Jack Cheung, Alfie Brennan, Benjamin Richard Bellenie, Owen Alexander Davis
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	1UU4 J0/U93 The present invention relates to compounds of formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: HN l Formula I wherein X1, X2 , R 1, R2 , R3 0, R31 and Ring A are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.