KRAS G12D MODULATING COMPOUNDS

Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.

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Bibliographische Detailangaben
Hauptverfasser: LAZERWITH, Scott E, DAI, Chaodi, TIAN, Maoqun, GUO, Hongyan, WATKINS, William J, PYUN, Hyung-Jung, ZAJDLIK, Adam D, MEDLEY, Jonathan William, GUERRERO, Juan A, KATO, Darryl, GUNEY, Tezcan, TSUI, Vickie H, KIBURU, Irene N, MCKINLEY, Jessica L, ZHANG, Jennifer R
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.