COMPOUNDS, COMPOSITIONS, AND METHODS

COMPOUNDS, COMPOSITIONS, AND METHODS

The present disclosure relates generally to small molecule modulators of NLR Family Pyrin Domain Containing 3 (NLRP3), or a pharmaceutically acceptable salt, isotopically enriched analog, stereoisomer, mixture of stereoisomers, or prodrug thereof, methods of making and intermediates thereof, and met...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FOX, Brian M, HUFFMAN, Benjamin J, ESTRADA, Anthony A, BAGDASARIAN, Alex L, DE VICENTE FIDALGO, Javier, CRAIG, II, OSIPOV, Maksim, LEXA, Katrina W, BUCHER, Cyril
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure relates generally to small molecule modulators of NLR Family Pyrin Domain Containing 3 (NLRP3), or a pharmaceutically acceptable salt, isotopically enriched analog, stereoisomer, mixture of stereoisomers, or prodrug thereof, methods of making and intermediates thereof, and methods of using thereof.