ONE-TO-STOP ATTENUATED SARS-COV-2 VIRUS

The invention relates to a polynucleotide encoding an attenuated SARS-CoV-2 or a fragment thereof, wherein the polynucleotide comprises at least 20 one-to-stop codons. The polynucleotide may comprise further modifications and may be comprised in an attenuated SARS-CoV-2. The invention further relate...

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Bibliographische Detailangaben
Hauptverfasser:	TRÜEB, Bettina Salome, THIEL, Volker, BEER, Martin, HALWE, Nico Joel, JORES, Jörg, EBERT, Nadine, BARUT, Güliz Tuba, ULRICH, Lorenz, SCHÖN, Jacob, HOFFMANN, Donata, KRATZEL, Annika, LABROUSSAA, Fabien
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a polynucleotide encoding an attenuated SARS-CoV-2 or a fragment thereof, wherein the polynucleotide comprises at least 20 one-to-stop codons. The polynucleotide may comprise further modifications and may be comprised in an attenuated SARS-CoV-2. The invention further relates to methods for production of the polynucleotide and pharmaceutical products, e.g. for medical use.