NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP USEFUL IN SEQUENCING BY SYNTHESIS

Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with an optionally substituted 3'vinyl blocking group. Also provided herein are methods to prepare such nucleotide and nucleoside molecules. Additionally, the present disclosure provides methods of using such bl...

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Bibliographische Detailangaben
Hauptverfasser:	RICHARD, Jean-Alexandre, TEO, Yin Nah, NEELAKANDAN, Ramesh, YANG, Xiangyuan, LUKAMTO, Daniel Hartoyo, NIRANTAR, Saurabh, SALAM, Sadeer, LIANG, Jing
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES DERIVATIVES THEREOF ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with an optionally substituted 3'vinyl blocking group. Also provided herein are methods to prepare such nucleotide and nucleoside molecules. Additionally, the present disclosure provides methods of using such blocked nucleosides and nucleotides in oligonucleotide synthesis and sequencing.