LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION

LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION

A liposome composition which comprises (A) liposomes containing dihydrosphingomyelin and a diacylglycerol-polyethylene glycol, (B) a drug and (C) a sulfate and/or sucrose octasulfate, and in which (A) encapsulates (B), wherein: the diacylglycerol-polyethylene glycol is distearoylglycerol-polyethylen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KATSURADA Yuri, TAKASE Yasutaka, MATSUMOTO Yasunobu, SUZUKI Takuya, ANDO Yuichiro, ONIZAWA Yuji, HYODO Kenji
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A liposome composition which comprises (A) liposomes containing dihydrosphingomyelin and a diacylglycerol-polyethylene glycol, (B) a drug and (C) a sulfate and/or sucrose octasulfate, and in which (A) encapsulates (B), wherein: the diacylglycerol-polyethylene glycol is distearoylglycerol-polyethylene glycol; and (B) is 4-(3-chloro-4-(ethylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide represented by formula (I) or pharmaceutically acceptable salt thereof.