SELF-ASSEMBLING PEPTIDES AND APPLICATIONS THEREOF

SELF-ASSEMBLING PEPTIDES AND APPLICATIONS THEREOF

The present invention belongs to the field of biomedical technology and relates to hydrogels for medical uses, in particular to a self-assembling peptide and applications thereof. The self assembling peptide provided by the present invention having an amino acid sequence shown as SEQ ID NO: 1, not o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHANG, Shang, BAI, Huan, LI, Gang, ZOU, Fangming, WANG, Pin, ZHU, Jinfeng, XIA, Yiran, CHENG, Yu, ZHAO, Chengru, LIU, Yuanxue, ZHANG, Linlin, GAO, Lichang, LI, Fangmin, ZHANG, Chunxia
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention belongs to the field of biomedical technology and relates to hydrogels for medical uses, in particular to a self-assembling peptide and applications thereof. The self assembling peptide provided by the present invention having an amino acid sequence shown as SEQ ID NO: 1, not only maintains a solution state under higher pH conditions but also has a acidity that is easily neutralized, thereby avoiding affecting the pH of body fluids in vivo. Additionally, it exhibits lower cytotoxicity and good cytocompatibility, while also demonstrating improved mechanical properties.