CELL CULTURE METHODS FOR ANTIBODY PRODUCTION

The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertain...

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Hauptverfasser:	CROWLEY, John, LAFOND, Michelle, OSHODI, Shadia Abike, GOH, Hai-Yuan, TANG, Xiaolin, CORBETT, Daniel, REILLY, James, VARTAK, Ankit, CHIBOROSKI, Mark, TUSTIAN, Andrew, STARLING, Alessandra, NICHOLL, Liam, HOURIHAN, John, WITMER, Ashley, MELLORS, Philip, STAIRS, Robert, MATTILA, John, JOHNSON, Amy S, BAK, Hanne, LAWRENCE, Shawn M, CASEY, Meghan, CALLINAN, Laura, CONLON, Aishling
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.