CAS12A NICKASES

CAS12A NICKASES

The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VILLEGAS WARREN, Ricardo, LUTEIJN, Maartje Janneke, D'HALLUIN, Katelijn, VAN DER OOST, John, MEULEWAETER, Frank, STAALS, Raymond Hubert Josèphe, WU, Wen Ying, DE VLEESSCHAUWER, David
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The present invention relates to the field of gene genome editing. In particular, it relates to the provision of a Cas12a enzyme having nickase activity, as well as the means and methods for the modification of a genomic locus of interest with a Cas12a enzyme having nickase activity and uses thereof.