FELINE ANTIBODY LIBRARY

The present invention relates to and provides polypeptide libraries, such as synthetic antibody libraries which are suitable for selection of fully feline antibodies. The invention also relates to synthetic nucleic acid sequences which encode individual or collections of feline antibodies, i.e. nucl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	WALDHUBER, Markus, BAER, Philipp, STERNER, Andrea
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMBINATORIAL CHEMISTRY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to and provides polypeptide libraries, such as synthetic antibody libraries which are suitable for selection of fully feline antibodies. The invention also relates to synthetic nucleic acid sequences which encode individual or collections of feline antibodies, i.e. nucleic acid sequences encoding feline antibody libraries. Methods for generating and using such libraries are provided. In particular, the invention relates to the preparation of a library of fully feline antibodies by the use of pre-evaluated synthetic sequences to generate a library of fully feline antibodies having favorable biophysical properties.