MODIFIED RELEASE VALPROIC ACID SOFTGEL CAPSULE

Softgel capsules comprise a fill composition and a shell composition, wherein the fill composition includes valproic acid and the shell composition includes gelatin, a plasticizer, and an enteric polymer. The softgel capsules further include from 125 mg to 1000 mg dosing of valproic acid. A method f...

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Bibliographische Detailangaben
Hauptverfasser: FANG, Qi, SUKURU, Karunakar
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Softgel capsules comprise a fill composition and a shell composition, wherein the fill composition includes valproic acid and the shell composition includes gelatin, a plasticizer, and an enteric polymer. The softgel capsules further include from 125 mg to 1000 mg dosing of valproic acid. A method for producing the softgel capsule using a gel mass and rotary die encapsulation is also provided.