ENVIRONMENTALLY RESPONSIVE MASKED ANTIBODY AND USE THEREOF

Provided is a masked antibody having better performance than conventional masked antibodies.　A molecule that binds to a target antigen, the molecule comprising the following part [a], part [b], and part [c]. Part [a]: A part that binds to the target antigen. Part [b]: A first peptide that recognizes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KUDO Shota, SAEKI Kazunori
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided is a masked antibody having better performance than conventional masked antibodies.　A molecule that binds to a target antigen, the molecule comprising the following part [a], part [b], and part [c]. Part [a]: A part that binds to the target antigen. Part [b]: A first peptide that recognizes the target antigen binding site included in part [a]. Part [c]: A second peptide composed of an amino acid sequence including an amino acid that changes from a negative charge to a positive charge in response to a change in pH from neutral to acidic in the pH range of 7.5 or lower.