Novel method for producing antibody-drug conjugate

Abstract A method for producing a compound represented by formula (C) wherein R' represents an amino group protected with a protecting group, the method comprising a step of subjecting a compound represented by formula (B) wherein R' represents the same meaning as above, to intramolecular...

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Hauptverfasser: Takeda, Tadahiro, Nishi, Yoshio, Sakanishi, Kohei, Noguchi, Shigeru
Format: Patent
Sprache:eng
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Zusammenfassung:Abstract A method for producing a compound represented by formula (C) wherein R' represents an amino group protected with a protecting group, the method comprising a step of subjecting a compound represented by formula (B) wherein R' represents the same meaning as above, to intramolecular cyclization to convert the compound into the compound represented by formula (C). Me O o Me0 (B) (C)