AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS

The invention relates to agents and methods for targeted delivery of payloads to cells. In some embodiments, the payload comprises a nucleic acid encoding an antigen receptor such as a T cell receptor (TCR) or chimeric antigen receptor (CAR). The agents and methods for targeted delivery of a nucleic...

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Hauptverfasser: WILDEMANN, Dirk, OTHERSEN, Olaf, KLINGER, Karl, APRICENO, Azzurra, KOCH, Klaus, KALLIN, Daniel, BOGEN, Jan Patrick, DONG, Zhengxin, RENGSTL, Benjamin, MCGEE, Jonathan, GANGLUFF, Meike, KUNA, Kathrin, SCHMOLDT, Hans-Ulrich, HELLER, Philipp, THANKI, Kaushik, WÜSTEHUBE-LAUSCH, Joycelyn, BILLMEIER, Arne Marten, KAPOOR, Tanya, KRESS, Christoph, HAAS, Heinrich
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to agents and methods for targeted delivery of payloads to cells. In some embodiments, the payload comprises a nucleic acid encoding an antigen receptor such as a T cell receptor (TCR) or chimeric antigen receptor (CAR). The agents and methods for targeted delivery of a nucleic acid encoding an antigen receptor described herein may be used for generating