FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS

The invention provides novel substituted heterocyclic compounds represented by the Formulas (I), or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as agonists of Stimulator o...

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Bibliographische Detailangaben
Hauptverfasser:	YOON, Cheolhwan, KIM, Sunjoo, LEE, Jungwoo, SEO, Jeongbeob, HAN, Cheolkyu, JEON, Sunhwa, JEON, Seeun, LEE, Jinwoo, YANG, Inho, KANG, Hongjun, KANG, Byungnam, SHIN, Youngdo
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides novel substituted heterocyclic compounds represented by the Formulas (I), or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as agonists of Stimulator of Interferon Genes (STING) and are useful in the treatment of cancers and certain infectious diseases.