Branched oligonucleotides

Provided herein are branched oligonucleotides exhibiting efficient and specific tissue distribution, cellular uptake, minimum immune response and off-target effects, without formulation.

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Bibliographische Detailangaben
Hauptverfasser: Godinho, Bruno Miguel da Cruz, Alterman, Julia, Hassler, Matthew, Khvorova, Anastasia
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided herein are branched oligonucleotides exhibiting efficient and specific tissue distribution, cellular uptake, minimum immune response and off-target effects, without formulation.