Multiplex amplification detection assay and isolation and detection of DNA from plasma

Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the 5 sample DNA. The technology further p...

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Bibliographische Detailangaben
Hauptverfasser: Giakoumopoulos, Maria, Kaiser, Michael W, Sander, Tamara J, Allawi, Hatim, Aizenstein, Brian, Vaccaro, Abram Michael, Gray, Melissa M, Lidgard, Graham P
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the 5 sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.