Therapeutic compositions for viral-associated disease states and methods of making and using same

Abstract Disclosed herein are methodologies and compositions useful for the treatment of subjects suffering from a viral-associated disease state that can result in immunosuppression, such as for example inaction with the Ebola virus, Marburg virus, and Hanta virus. Hereinafter, such viruses which cause an infection that can result in immunosuppressive events in the infected subject are collectively termed viruses-associated with immunosuppressive events (VISE). Also disclosed herein are apparatuses useful in the treatment of subjects suffering from a VISE. In an embodiment, the compositions disclosed herein comprise adsorbent materials that are utilized in conjunction with one or more apparatuses of the type disclosed herein in the treatment of subject suffering from a WO 2016/049483 PCT/US2015/052272 39 2 -~\ ack To 395 378-A 340 342 the Patient 376 -X 345 - X IG V 385 370 -' 310 375 C B A 39 0 355 305 362 -- X 352-- X 3 5 0 V-380 the Patient 315 360 348 780- 1/o SECONDARY CPU RAM 788 784 782 ROM 786