Neural precursor cell populations and uses thereof

The present invention provides cell populations enriched for specific neural precursor markers and methods of using such cell populations for treatment of disorders associated with dysregulation of inhibitory neuronal function and/or imbalances in excitatory/inhibitory neuronal activity. In particul...

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Bibliographische Detailangaben
Hauptverfasser: Bershteyn, Marina, Kriks, Sonja, Nicholas, Cory, Fuentealba, Luis, Tong, Cheuk Ka, Chambers, Stuart
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides cell populations enriched for specific neural precursor markers and methods of using such cell populations for treatment of disorders associated with dysregulation of inhibitory neuronal function and/or imbalances in excitatory/inhibitory neuronal activity. In particular, the present invention provides cell populations for use as a cell-based therapeutic, and methods for purification and use of these neural precursor cells in transplantation to ameliorate neural disorders associated with aberrant neural function.