APTAMERS FOR THE REVERSIBLE INHIBITION OF DNA POLYMERASES

Described herein are methods and compositions for improved polymerase chain reaction (PCR). In one aspect the methods and compositions include improved aptamers to reversibly inhibit polymerase and exonuclease activity of the polymerase enzyme.

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Bibliographische Detailangaben
Hauptverfasser: CAGLE, Brianna, RUPP, Susan Marie, SHUBHAM, Shambhavi, ROSE, Scott
Format: Patent
Sprache:eng
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Zusammenfassung:Described herein are methods and compositions for improved polymerase chain reaction (PCR). In one aspect the methods and compositions include improved aptamers to reversibly inhibit polymerase and exonuclease activity of the polymerase enzyme.