SUSTAINED RELEASE INJECTABLE PHARMACEUTICAL FORMULATION OF LEVOTHYROXINE AND PROCESS FOR PREPARATION THEREOF

The present invention relates to a stable sustained release injectable formulation based on poly(D,L-lactide-co-glycolide) microparticles comprising Levothyroxine. It also relates to a process for the preparation of microparticles and use to control hypothyroidism in adults, congenital hypothyroidis...

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Bibliographische Detailangaben
Hauptverfasser: KATSENIS, Athanasios, PAPADAKI, Anna, KOUTRIS, Efthymios, KALANTZI, Lida, KOTTI, Katerina, KALEZI, Artemis, BRIEUDES, Vincent, KARAVAS, Evangelos, CHAITIDOU, Sotiria, LEMONAKIS, Nikos
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to a stable sustained release injectable formulation based on poly(D,L-lactide-co-glycolide) microparticles comprising Levothyroxine. It also relates to a process for the preparation of microparticles and use to control hypothyroidism in adults, congenital hypothyroidism in infants and acquired hypothyroidism in children.