COMPOSITION FOR ENHANCING ACTIVITY OF NATURAL KILLER CELLS

The present invention relates to a composition for enhancing the activity of natural killer cells, and provides a composition for enhancing the activity of natural killer cells, the composition containing, as an active ingredient, a peptide having an amino acid sequence of SEQ ID NO: 1. The peptide...

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Bibliographische Detailangaben
Hauptverfasser:	YOON, Suk Ran, KIM, Hanna, BYUN, Jae Eun, CHOI, In Pyo, JUNG, Haiyoung
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a composition for enhancing the activity of natural killer cells, and provides a composition for enhancing the activity of natural killer cells, the composition containing, as an active ingredient, a peptide having an amino acid sequence of SEQ ID NO: 1. The peptide having the amino acid sequence of SEQ ID NO: 1 according to the present invention not only increases the cell killing ability of natural killer cells but also reduces the fratricide increased by TGF-β, and further improves the sensitivity of the natural killer cells to cancer cells. Thus, the peptide having the amino acid sequence of SEQ ID NO: 1 can be effectively used as an active ingredient for an anticancer drug or an anticancer adjuvant.