APOLIPOPROTEIN FUSION PROTEINS FOR CELL-SPECIFIC IMMUNE REGULATION

The invention relates to fusion proteins of apolipoprotein with an immunomodulatory biomolecule and/or a rerouting molecule. The fusion proteins can be used as a carrier for an immunomodulatory biomolecule as such or incorporated in a lipid nanoparticle. The fusion protein finds use in the treatment...

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Bibliographische Detailangaben
Hauptverfasser: VAN DER MEEL, Roy, DE DREU, Anne, MULDER, Willem J.M, MERKX, Maarten, SCHRIJVER, David Pepijn, HOKKE, Ayla Martine, DE BRUIN, Koen
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to fusion proteins of apolipoprotein with an immunomodulatory biomolecule and/or a rerouting molecule. The fusion proteins can be used as a carrier for an immunomodulatory biomolecule as such or incorporated in a lipid nanoparticle. The fusion protein finds use in the treatment of immune related disorders, or targeting a payload to a specific target site.