COMPOSITIONS COMPRISING A CRISPR NUCLEASE AND USES THEREOF

The present disclosure relates to variant polypeptides, methods of preparing the variant polypeptides, processes for characterizing the variant polypeptides, compositions and cells comprising the variant polypeptides, and methods of using the variant polypeptides. The disclosure further relates to c...

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Bibliographische Detailangaben
Hauptverfasser: CHONG, Shaorong, ALFONSE, Lauren E, JAKIMO, Noah Michael, WESSELLS, Quinton Norman, GARRITY, Anthony James, ZIBLAT, Roy
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure relates to variant polypeptides, methods of preparing the variant polypeptides, processes for characterizing the variant polypeptides, compositions and cells comprising the variant polypeptides, and methods of using the variant polypeptides. The disclosure further relates to complexes comprising the variant polypeptides, methods of producing the complexes, processes for characterizing the complexes, cells comprising the complexes, and methods of using the complexes.