HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS

One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BRUBAKER, Jason, CLOSE, Joshua, DINEEN, Thomas, MIDUTURU, Chandrasekhar, PEROLA, Emanuele
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator BRUBAKER, Jason
CLOSE, Joshua
DINEEN, Thomas
MIDUTURU, Chandrasekhar
PEROLA, Emanuele
description One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from control of MAP4K1 activity.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2022312496A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2022312496A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2022312496A13</originalsourceid><addsrcrecordid>eNrjZND2cA1xDfJ3jnT28XRWcPb3DfAP9XMJVnAMVvB1DDDxNlTw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8Y6hRgZGRsaGRiaWZo6GxsSpAgAE_iWz</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS</title><source>esp@cenet</source><creator>BRUBAKER, Jason ; CLOSE, Joshua ; DINEEN, Thomas ; MIDUTURU, Chandrasekhar ; PEROLA, Emanuele</creator><creatorcontrib>BRUBAKER, Jason ; CLOSE, Joshua ; DINEEN, Thomas ; MIDUTURU, Chandrasekhar ; PEROLA, Emanuele</creatorcontrib><description>One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from control of MAP4K1 activity.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240222&amp;DB=EPODOC&amp;CC=AU&amp;NR=2022312496A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240222&amp;DB=EPODOC&amp;CC=AU&amp;NR=2022312496A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BRUBAKER, Jason</creatorcontrib><creatorcontrib>CLOSE, Joshua</creatorcontrib><creatorcontrib>DINEEN, Thomas</creatorcontrib><creatorcontrib>MIDUTURU, Chandrasekhar</creatorcontrib><creatorcontrib>PEROLA, Emanuele</creatorcontrib><title>HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS</title><description>One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from control of MAP4K1 activity.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND2cA1xDfJ3jnT28XRWcPb3DfAP9XMJVnAMVvB1DDDxNlTw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8Y6hRgZGRsaGRiaWZo6GxsSpAgAE_iWz</recordid><startdate>20240222</startdate><enddate>20240222</enddate><creator>BRUBAKER, Jason</creator><creator>CLOSE, Joshua</creator><creator>DINEEN, Thomas</creator><creator>MIDUTURU, Chandrasekhar</creator><creator>PEROLA, Emanuele</creator><scope>EVB</scope></search><sort><creationdate>20240222</creationdate><title>HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS</title><author>BRUBAKER, Jason ; CLOSE, Joshua ; DINEEN, Thomas ; MIDUTURU, Chandrasekhar ; PEROLA, Emanuele</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2022312496A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BRUBAKER, Jason</creatorcontrib><creatorcontrib>CLOSE, Joshua</creatorcontrib><creatorcontrib>DINEEN, Thomas</creatorcontrib><creatorcontrib>MIDUTURU, Chandrasekhar</creatorcontrib><creatorcontrib>PEROLA, Emanuele</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BRUBAKER, Jason</au><au>CLOSE, Joshua</au><au>DINEEN, Thomas</au><au>MIDUTURU, Chandrasekhar</au><au>PEROLA, Emanuele</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS</title><date>2024-02-22</date><risdate>2024</risdate><abstract>One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from control of MAP4K1 activity.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_AU2022312496A1
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T08%3A29%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BRUBAKER,%20Jason&rft.date=2024-02-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2022312496A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true