HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS

HETEROCYCLIC COMPOUNDS AS MAP4K1 INHIBITORS

One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BRUBAKER, Jason, CLOSE, Joshua, DINEEN, Thomas, MIDUTURU, Chandrasekhar, PEROLA, Emanuele
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:One embodiment of the disclosure is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof. The variables in Formula (I) are defined herein. Compounds of Formula (I) are MAP4K1 inhibitors, which can be used to treat a diseases or disorders in a subject that benefits from control of MAP4K1 activity.