USE OF ANTI-CTLA-4 ANTIBODY

The present disclosure provides anti-CTLA-4 antibodies and methods of producing and using the antibodies. The present disclosure also provides nucleic acids encoding the anti-CTLA-4 antibodies and host cells containing the nucleic acids. Furthermore, the present disclosure provides polypeptides cont...

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Bibliographische Detailangaben
Hauptverfasser: HORI, Yuji, SUSUMU, Hiroaki, KAMIMURA, Masaki, KAWAUCHI, Hiroki, SAKAGUCHI, Shimon, TATSUMI, Kanako, KATADA, Hitoshi, HAYASHI, Hiroki, SHIMIZU, Shun, IGAWA, Tomoyuki, MATSUDA, Yutaka, KOMORI, Yasunori
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides anti-CTLA-4 antibodies and methods of producing and using the antibodies. The present disclosure also provides nucleic acids encoding the anti-CTLA-4 antibodies and host cells containing the nucleic acids. Furthermore, the present disclosure provides polypeptides containing a variant Fc region containing amino acid alterations in a parent Fc region and methods of producing and using the polypeptides.