Multivalent and multispecific DR5-binding fusion proteins

Multivalent and multispecific DR5-binding fusion proteins

The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.

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Bibliographische Detailangaben
Hauptverfasser: JONES, Kyle S, HUSSAIN, Abrahim, TIMMER, John C, RAZAI, Amir S, WILLIS, Katelyn M, DEVERAUX, Quinn, ECKELMAN, Brendan P
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.