ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF CANCER

The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): (I) or pharmaceutically acceptable salts thereof wherein R, R

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Bibliographische Detailangaben
Hauptverfasser:	DAWADI, Surendra, ANDERSON, Erin Danielle, HICKEY, Eugene R, CHEN, Xiaohong, POTOTSCHNIG, Gerit Maria, KOLAKOWSKI, Gabrielle R, MCLEAN, Johnathan Alexander, WIDJAJA, Tien, IRVIN, Thomas Combs, WELCH, Michael Brian, LONG, Katelyn Frances, ARONOW, Sean Douglas, KNIGHT, Jennifer Lynn, WANG, Hua-Yu, BOYLES, Nicholas A, KUMAR, Manoj, MAYNE, Christopher Glenn, KESICKI, Edward A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): (I) or pharmaceutically acceptable salts thereof wherein R, R