Oil-based adjuvants

Abstract The instant invention provides various formulations comprising combinations of immunostimulating oligonuc leotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunog...

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Bibliographische Detailangaben
Hauptverfasser:	FOSS, Dennis L, GALLO, Guillermo, RAI, Sharath K, DOMINOWSKI, Paul Joseph, WILMES, Lauren, LIGHTLE, Sandra Ann Marie, MOHR, Kaori, SMITH, David George Emslie, MWANGI, Duncan, FITZPATRICK, Julie Lydia, MAHAN, Suman, SALMON, Sarah A, VORA, Shaunak, KREBS, Richard Lee, MEDIRATTA, Sangita, FONTAINE, Michael Christopher, JAGLARZ, Anita Dorota, HARDHAM, John Morgan, DONACHIE, William
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Abstract The instant invention provides various formulations comprising combinations of immunostimulating oligonuc leotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.