ENGINEERED CELLS FOR INCREASED PRODUCTION OF DIFFICULT-TO-EXPRESS PROTEINS

ENGINEERED CELLS FOR INCREASED PRODUCTION OF DIFFICULT-TO-EXPRESS PROTEINS

Described are engineered cells that include genetic alterations leading to up- or down- regulation of certain genes in the cells for improved production of a recombinant protein, especially one that is not easily expressed at high levels in unaltered cell lines. Also provided are methods of preparin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: GOEL, Nikhil
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Described are engineered cells that include genetic alterations leading to up- or down- regulation of certain genes in the cells for improved production of a recombinant protein, especially one that is not easily expressed at high levels in unaltered cell lines. Also provided are methods of preparing and using such cells.