ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE

The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3 -kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I) or pharmaceutically acceptable salts thereof wherein R, R

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Bibliographische Detailangaben
Hauptverfasser:	DAWADI, Surendra, ARONOW, Sean, KOLAKOWSKI, Gabrielle, CHEN, Xiaohong, HICKEY, Eugene, LONG, Katelyn, WELCH, Michael, WIDJAJA, Tien, ANDERSON, Erin, WRIGHT, Nathan, WANG, Hua-Yu, KESICKI, Edward, IRVIN, Thomas, MAYNE, Christopher, PICADO, Alfredo, POTOTSCHNIG, Gerit, KUMAR, Manoj, BOYLES, Nicholas, KNIGHT, Jennifer
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3 -kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I) or pharmaceutically acceptable salts thereof wherein R, R