ANTI-C-MET ANTIBODIES AND ANTIBODY-DRUG CONJUGATES

The present invention relates to antibodies or antigen-binding fragments thereof that specifically bind to the mesenchymal-epithelial transition factor (c-Met). The invention additionally relates to antibody drug conjugates (ADCs) comprising these anti-c-Met antibodies or antigen-binding fragments,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BLOMENRÖHR, Marion, VAN DER LEE, Miranda Maria Cornelia, GROOTHUIS, Patrick Gerhard
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to antibodies or antigen-binding fragments thereof that specifically bind to the mesenchymal-epithelial transition factor (c-Met). The invention additionally relates to antibody drug conjugates (ADCs) comprising these anti-c-Met antibodies or antigen-binding fragments, pharmaceutical compositions comprising the antibodies, antigen-binding fragments or ADCs, and the use thereof in the treatment of cancer.