USE OF A BET INHIBITOR ALONE OR IN COMBINATION WITH FEDRATINIB OR RUXOLITINIB FOR TREATING A HEMATOLOGICAL MALIGNANCY SUCH AS MYELOFIBROSIS

The present disclosure provides methods, pharmaceutical compositions, and kits for treating cancer in patients in need thereof. The methods comprise administering to a patient in need a BET (bromodomain and extra-terminal protein) inhibitor, or a pharmaceutically acceptable salt thereof, alone or in...

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Bibliographische Detailangaben
Hauptverfasser:	DAS, Sharmila, CARRANCIO ANTON, Maria Soraya, COKER, Shodeinde, LIU, Yu, ARONCHIK, Ida, GUARINOS MARHUENDA, Carla, FILVAROFF, Ellen Hope, NIKOLOVA, Zariana, HANNA, Bishoy, BELTRAN VALENCIA, Roxxana Valeria, ESPOSITO, Oriana, CHANG, Henry H
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides methods, pharmaceutical compositions, and kits for treating cancer in patients in need thereof. The methods comprise administering to a patient in need a BET (bromodomain and extra-terminal protein) inhibitor, or a pharmaceutically acceptable salt thereof, alone or in combination with one or more JAK inhibitors. Also provided are medicaments for use in treating cancer.