FREEZE-DRIED PLATELET DERIVATIVE COMPOSITIONS FOR TREATING ANTIPLATELET-INDUCED COAGULOPATHY

Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illust...

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Bibliographische Detailangaben
Hauptverfasser: ISHLER, Braden Carl, LEE, Amber Nicole, MATHEWS, Michael Alexander, JORDA, Rafael, MOSKOWITZ, Keith Andrew, DICKERSON, William Matthew, TANDON, Narendra Nath, AMOS, Stephen Edward
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.