COMPLEMENT C3 ANTIGEN BINDING PROTEINS

Antigen-binding proteins with specificity to complement C3 and C3b are provided.Methods of treating complement C3-mediated diseases and disorders, methods of inhibiting the activity of the complement Classical pathway (CP), Lectin pathway (LP), and/or Alternative pathway (AP), and methods of inhibit...

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Hauptverfasser: LEISNER, Christian, BORRAS, Leonardo, SCHEIFELE, Fabian, ESCHER, Dominik, JUNGMICHEL, Stephanie, RICHLE, Philipp Robert
Format: Patent
Sprache:eng
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Zusammenfassung:Antigen-binding proteins with specificity to complement C3 and C3b are provided.Methods of treating complement C3-mediated diseases and disorders, methods of inhibiting the activity of the complement Classical pathway (CP), Lectin pathway (LP), and/or Alternative pathway (AP), and methods of inhibiting the activity of choroidal-localized complement C3 are also provided.