LACTAMS AS CBL-B INHIBITORS

Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same. Representative lactam compounds include molecules falling within the following formulae:

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Hauptverfasser: JAKALIAN, Araz, YADAV, Arun, BROCCATELLI, Fabio, LAMBRECHT, Michael John, LAROUCHE-GAUTHIER, Robin, WANG, Xiaojing, LIANG, Jun, UNG, Man Un, ZBIEG, Jason Robert, HUESTIS, Malcolm
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creator JAKALIAN, Araz
YADAV, Arun
BROCCATELLI, Fabio
LAMBRECHT, Michael John
LAROUCHE-GAUTHIER, Robin
WANG, Xiaojing
LIANG, Jun
UNG, Man Un
ZBIEG, Jason Robert
HUESTIS, Malcolm
description Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same. Representative lactam compounds include molecules falling within the following formulae:
format Patent
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title LACTAMS AS CBL-B INHIBITORS
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