GENETICALLY ENGINEERED CELLS AND METHODS OF MAKING THE SAME

GENETICALLY ENGINEERED CELLS AND METHODS OF MAKING THE SAME

Abstract Provided are CRISPR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequence, and applications thereof in connection with cancer immunotherapy comprising adoptive transfer of engineered T cells or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bumcrot, David A, Salmon, Ruth, Nye, Chris, Maeder, Morgan L, Rubio, Eugenio Marco, Welstead, G. Grant, Friedland, Ari E, Sather, Blythe, Jones, Jon
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Abstract Provided are CRISPR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequence, and applications thereof in connection with cancer immunotherapy comprising adoptive transfer of engineered T cells or T cell precursors.