MATERIALS AND METHODS FOR MONITORING CANCER BY ADMINISTERING AN ANTI-MCL1 ANTIBODY

The disclosure provides anti-Mcl-1 antibodies of any form, and fragments thereof, that bind the antigen with unexpectedly high binding to Mcl-1, providing tools useful in methods of monitoring cancer cells expressing Mcl-1 and methods of treating cancers, particularly blood- borne cancers, comprisin...

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Bibliographische Detailangaben
Hauptverfasser: BOYLE, Michael C, CHAN, Brian, KIELCZEWSKA, Agnieszka
Format: Patent
Sprache:eng
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Zusammenfassung:The disclosure provides anti-Mcl-1 antibodies of any form, and fragments thereof, that bind the antigen with unexpectedly high binding to Mcl-1, providing tools useful in methods of monitoring cancer cells expressing Mcl-1 and methods of treating cancers, particularly blood- borne cancers, comprising such cancer cells.