Aryl, Heteroary, And Heterocyclic Pharmaceutical Compounds For Treatment Of Medicinal Disorders

Aryl, Heteroary, And Heterocyclic Pharmaceutical Compounds For Treatment Of Medicinal Disorders

< Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chen, Dawei, Wang, Qiuping, Eastman, Kyle J, Phadke, Avinash S, Gadhachanda, Venkat Rao, Greenlee, William, Agarwal, Atul, Wang, Xiangzhu, Hashimoto, Akihiro, Deshpande, Milind, Wiles, Jason Allan, Pais, Godwin, Barrish, Joel Charles
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:< Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and ~ 0 inhibit or regulate the complement cascade. -.::j'"