NON-STOP PRODUCTION PROCESS FOR IMPROVING FREEZE-DRYING SURVIVAL, HEAT TOLERANCE, SHELF STABILITY AND DIGESTIVE STABILITY OF PROBIOTICS USING SPONTANEOUS MATRIX-ENCAPSULATION TECHNIQUE

The present invention relates to a non-stop production process for encapsulated probiotics, wherein the encapsulation process of probiotics can be remarkably improved by allowing the probiotics to be encapsulated in alginate hydrogel spontaneously formed through a simple process of culturing probiot...

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Bibliographische Detailangaben
Hauptverfasser: LEE, Sunghee, KIM, Young-Hoo, KIM, Hyeong-Eun, KIM, Tae-Yoon, HAN, Chi-Young, SEO, Han Sol
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to a non-stop production process for encapsulated probiotics, wherein the encapsulation process of probiotics can be remarkably improved by allowing the probiotics to be encapsulated in alginate hydrogel spontaneously formed through a simple process of culturing probiotics in a medium containing alginate, a salt, preferably an insoluble carbonate, which binds with alginic acid to form a hydrogel, and, optionally, an encapsulation enhancer, and the freeze-drying survival, heat tolerance, shelf stability, and digestive stability (acid resistance, bile resistance) of the probiotics are significantly improved.