SONOGENETIC STIMULATION OF CELLS EXPRESSING A HETEROLOGOUS MECHANOSENSITIVE PROTEIN

Provided and described are mechanosensory polypeptides and encoding polynucleotide products and compositions thereof, methods of expressing such polypeptides and polynucleotides in a cell type of interest, and methods of inducing and/or modifying the activity and/or function of various types of cell...

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Hauptverfasser: CHALASANI, Sreekanth, RAMIREZ, Marc Duque, MURTHY, Swetha, PATAPOUTIAN, Ardem, PATEL, Janki, LEE-KUBLI, Corinne, CHORY, Joanne, MOUSAVI, Seyed Ali Reza, LOPEZ, Jose Mendoza, TUFAIL, Yusuf, PROCKO, Carl, KEENAN, William T
Format: Patent
Sprache:eng
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Zusammenfassung:Provided and described are mechanosensory polypeptides and encoding polynucleotide products and compositions thereof, methods of expressing such polypeptides and polynucleotides in a cell type of interest, and methods of inducing and/or modifying the activity and/or function of various types of cells that express the exogenous mechanosensory polypeptides using ultrasound.